L-Carnitine

What is L-Carnitine?

L-Carnitine is a naturally occurring amino acid derivative that plays a critical role in energy metabolism, specifically in the transport of long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation. It is biosynthesized in the body from the amino acids lysine and methionine, with vitamin C, niacin, and vitamin B6 also required for its endogenous synthesis. Red meat and dairy products are the primary dietary sources of L-Carnitine. Only the L-form (levocarnitine) is biologically active. L-Carnitine is widely used across food, beverage, and nutritional supplement manufacturing due to its multifunctional properties, which include:

  • Energy Metabolism Support: Facilitates the transport of long-chain fatty acids into the mitochondria, where they are oxidized to produce ATP. This function underpins its use in sports nutrition, weight management, and energy products.
  • Sports & Exercise Recovery: Supplementation is associated with reduced exercise-induced muscle soreness, improved oxygen utilization, and enhanced post-workout fat oxidation, making it a popular ingredient in pre- and post-workout formulations.
  • Cardiovascular Health Support: Research indicates that L-Carnitine supplementation may support cardiovascular function by improving myocardial energy metabolism and reducing oxidative stress in cardiac tissue.
  • Weight Management Formulations: By promoting fat utilization as a fuel source, L-Carnitine is frequently included in weight management supplements, functional beverages, and meal replacement products.
  • Infant Nutrition & Clinical Nutrition: L-Carnitine is an essential additive in infant formula and clinical nutrition products, particularly for premature infants whose endogenous synthesis capacity is limited. It is also used in renal and metabolic disorder dietary support.

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L-Carnitine Technical & Product Specifications

Characteristic

Specification

Chemical Name/Synonyms L-Carnitine (Levocarnitine, Vitamin BT, (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt)
CAS Number 541-15-1
Molecular Formula/Weight C₇H₁₅NO₃ / 161.20 g/mol
Appearance White or almost white crystalline powder or colorless crystals; hygroscopic
Odor/Taste Characteristic; essentially odorless
Decomposition Point Approximately 185 degrees C to 195 degrees C (decomposes without melting)
Solubility Freely soluble in water; soluble in warm ethanol; practically insoluble in acetone and ethyl acetate
pH (aqueous solution) Approximately 5.5 to 9.5 (10% aqueous solution)
Typical Assay (Purity) 97.0% to 103.0% (anhydrous basis, USP); 98.0% to 102.0% (anhydrous, FCC)
Regulatory/Grade FCC Grade, USP Grade; Kosher certification available
Packaging Options 25kg / 55lb bags; additional configurations available upon request
Microbial Limits Conforms to FCC / USP food safety standards

Regulatory & Handling Considerations

  • Food Regulatory Approvals: L-Carnitine Crystalline and L-Carnitine L-Tartrate have self-affirmed GRAS (Generally Recognized As Safe) status for use at defined levels in specific food categories including energy drinks, fruit juices, protein bars, meal replacements, health bars, and imitation dairy products in the U.S. L-Carnitine is also authorized in infant formula under 21 CFR Part 107. In the EU, it is authorized as a food additive for particular nutritional uses (infant formula, follow-on formula, and foods for special medical purposes) under applicable EU regulations.
  • Stability: L-Carnitine is thermally stable at temperatures above 200 degrees C, making it compatible with most food processing conditions including high-temperature manufacturing. However, it is hygroscopic; exposure to moisture should be minimized. Store in sealed containers in a cool, dry environment.
  • Ingredient Interactions: L-Carnitine is compatible with most beverage, supplement, and food matrix ingredients. Its high water solubility makes it easy to incorporate into liquid formulations. No significant adverse interactions with common food ingredients have been identified at typical use levels.
  • Labeling: Must be declared on ingredient labels as ‘L-Carnitine’ or ‘Levocarnitine’ in the U.S. per applicable FDA labeling regulations. When used as a nutrient in dietary supplements, it must comply with 21 CFR Part 101 supplement labeling requirements.

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Benefits of L-Carnitine for Food & Beverage Manufacturers

  • Supports on-trend formulations in sports nutrition, weight management, and functional beverages
  • High water solubility enables easy incorporation into liquid, powder, and bar formats
  • Thermally stable under typical food processing temperatures
  • Supports substantiated claims relating to energy metabolism, athletic performance, and cardiovascular health
  • Available in multiple forms (crystalline, L-Tartrate) to suit diverse formulation and label requirements
  • Meets global food-grade standards (FCC, USP) for safety and purity

About American International Foods, Inc. (AIFI) - A L-Carnitine Supplier & Distributor

American International Foods, Inc. is a leading L-Carnitine supplier with an additional full-service portfolio of over 2500 food and beverage ingredients. We offer one of the most extensive lines of amino acids distributed to manufacturers and processors in the food, beverage, pet food, health and nutrition sectors. With a strategic nationwide warehouse network and our reliable just-in-time deliveries, we can supply your business with high quality amino acids at competitive prices.